TCA is a chemical cauterant the application of which to the skin causes protein denaturation, so called keratocoagulation, resulting in a readily observed white frost. TCA peel can be used for epidermal growths including actinic keratoses and thin seborrheic keratoses, mild to moderate photoaging, pigmentary dyschromias including melasma and post-inflammatory hyperpigmentation, pigmented lesions including lentigines and ephelides, acne and acne scarring.
TCA peels confer several advantages. TCA does not have any systemic toxicity. In addition, it is a versatile agent that can be used for superficial, medium and deep chemical peeling. The frosting reaction can be a utilized as a reliable indicator for the depth of the chemical peel, making this a safe agent in the hands of the experienced dermatologist.