Androgenentic alopecia (AGA) is the most common cause of hair loss. It affects at least 50% of men by the age of 50 years. Although the condition is so frequent that it is sometimes considered a physiological sign of aging, it causes considerable discomfort to patients and has been proven to impair their quality of life.
A novel method of promoting hair growth by application of a blood extract is an interesting and upcoming safe, easy and inexpensive modality to treat AGA.
Platelet Rich Plasma (PRP) is an autologous concentration of human platelets in a small volume of plasma that has a higher platelet concentration (4–7-times) above baseline. It contains a large array of growth factors like PDGF, VEGF, epidermal growth factor (EGF), fibroblast growth factor-2 (FGF-2), and insulin-like growth factor (IGF). PRP is being widely used in a number of medical and surgical specialties to enhance tissue repair and healing.
Its potentiality to promote hair growth in areas containing hair follicles is known since 1900. The various growth factors present in PRP promote hair production by inducing the follicular stem cells to shift from a dormant state to an active state. Also, VEGF-8 and PDGF-4 facilitate angiogenesis around the hair follicle, thus promoting hair production.
PRP is a highly effective treatment option for hair loss, hair thinning and hair damage. It produces great results by increasing the thickness of the existing hairs. It is a very safe treatment without any side effects and allergic reactions.